Mammalian cell functions mediating recombination of genetic elements
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چکیده
منابع مشابه
Recombination between IS5 elements: requirement for homology and recombination functions.
Intermolecular recombination between two IS5 elements was measured, using bacteriophage lambda recombination vectors, and was compared to recombination between two copies of an SV40 segment cloned into the same vectors. Experiments were conducted in the presence and in the absence of RecA and Red functions, and with the recombining inserts in the same or in reversed orientation. Under all condi...
متن کاملMeiotic recombination between duplicated genetic elements in Saccharomyces cerevisiae.
We have studied the meiotic recombination behavior of strains carrying two types of duplications of an 18.6-kilobase HIS4 Bam HI fragment. The first type is a direct duplication of the HIS4 Bam HI fragment in which the repeated sequences are separated by Escherichia coli plasmid sequences. The second type, a tandem duplication, has no sequences intervening between the repeated yeast DNA. The HI...
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Small nucleolar RNAs (snoRNAs) of the H/ACA box and C/D box categories guide the pseudouridylation and the 2'-O-ribose methylation of ribosomal RNAs by forming short duplexes with their target. Similarly, small Cajal body-specific RNAs (scaRNAs) guide modifications of spliceosomal RNAs. The vast majority of vertebrate sno/scaRNAs are located in introns of genes transcribed by RNA polymerase II ...
متن کاملCorrection: Mammalian Small Nucleolar RNAs Are Mobile Genetic Elements
Michel J. Weber doi:10.1371/journal.pgen.0020205 In PLoS Genetics, volume 2, issue 12: In the Materials and Methods, the URL to the Yass online program was incorrectly listed. The correct URL is http:// bioinfo.lifl.fr/yass/yass.php. This correction note may be found online at doi:10.1371/journal.pgen.0030036 Published February 23, 2007 Citation: (2007) Correction: Mammalian small nucleolar RNA...
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Mouse LTKcells were transfected with a pair of defective Herpes simplex virus thymidine kinase ( t k ) genes. One tk gene had an 8-bp insertion mutation while the second gene had a 100-bp inversion. Extrachromosomal homologous recombination leading to the reconstruction of a functional tk gene was monitored by selecting for tk positive cells using medium supplemented with hypoxanthine/ aminopte...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1980
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/8.23.5835